Recurrence of Minimal Change Disease Following a Motor Vehicle Trauma: An Atypical Cause and Review of Literature
Jayaramakrishna Depa, M.D., George Coritsidis, M.D.
Department of Nephrology, Elmhurst Hospital Center, Icahn School of Medicine at Mount Sinai, Elmhurst, NY, USA
Correspondence to: Jayaramakrishna Depa, M.D. Department of Nephrology, Elmhurst Hospital Center, 79-01 Broadway, Queens, NY 11373, USA Tel: +1-718-334-3930 Fax: +1-718-334-5160 E-mail: sonu.reddy35@gmail.com
Received October 17, 2018; Revised December 19, 2018; Accepted February 7, 2019.
- Abstract
- Minimal change disease (MCD) in children has a favorable long-term prognosis, and development of end-stage renal disease is very uncommon; less than 5%. In the first case of its kind, we report a 21-year-old female with a history of MCD at the age of 6, who had late relapse subsequent to a motorcycle accident resulting in a de-gloving skin injury and intensive care unit admission. MCD was confirmed by normal light microscopy, podocyte effacement on electron microscopy and absence of any deposits on immunofluorescence 3 weeks after the incident due to critical illness. It is postulated that the skin injury is what caused the relapse of MCD.
- Keywords : Minimal change disease; Skin injury; Recurrence; Nephrology; End-stage renal disease
- March 2020, 33 (1)
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